Wrinkles that occur in facial skin have a lot of causes. They are just a part of aging in most cases. Skin that loses fat, elastin and collagen can also be a result of over exposure to the sun or repetitive facial gestures. Also, the skin will lose its ability to seal in moisture and the result of this is dry, shriveled looking skin because of dead skin cells. Underlying facial muscles can be forced to lay in a position they have been trained to over time and cause smile lines, frown lines, eyebrow lines and forehead lines. Crow’s feet lines may also start to appear.
In anti-aging creams, the objective is to keep the lines and wrinkles from forming in the first place, and in the case of anti-wrinkle creams, the purpose is to try to retrain the skin cells, to retain moisture and skin muscles to relax the positions they have formed over the years to cause certain skin wrinkles, as in the smiles lines and crow’s feet. There are methods of “rebuilding the skin structure” or “remodeling skin cells”, as it has been referred to. It usually involves the use of peptides, which is a wound healing process, much like in the case of burn victims, where the skin is remodeled to encourage new skin growth.
In the case of facial and skin muscle regrowth or retraining, peptides have been used, as a sort of muscle relaxer, as peptides tend work on a deeper level than some topical cream treatments. Argireline is a trade name for Acetyl Hexapeptide-3, which as the name implies is a peptide, a synthetic anti-aging chemical derived from natural proteins, making a chain of amino acids, which can be used to stimulate muscle relaxation and reflex reactions, that can be the underlying cause of a wrinkle appearing in a certain position over time.
Argireline is very successful at reducing muscle relaxations over time. Improvement begins at the 4 weeks period, with the effect double over 27 weeks. However, just like all other anti-wrinkle cream and anti-aging creams, once you stop using the product the wrinkle begin to reappear again.
Argireline treats the underlying muscles against normal treatment of the surface skin cells. This makes it a lot like a topical form of what Botox does. The cessation of the facial muscle contractions is a short-term solution, even with Botox. Makers of Argireline use less than a 10% ingredient content as a higher level could have side effects, like relaxing the facial muscles too much and creating sagging. While Argireline has not been on the market for long time, long-term effects have not been measured. It is an effective ingredient in topical anti-aging creams and anti-wrinkle creams and is sold in many formulations.