Anti aging, Skin care

The Best Anti-Wrinkle Cream Ingredients You Should Look For

Fed up with wrinkle creams that claim to be the best wrinkle cream on the face of the earth? Don’t fret—you are only one of the millions of women, and yes men, who are constantly on the lookout for the best wrinkle cream out there. This is because as you age, your skin will naturally lose most of its elasticity and moisture content.

Once this occurs, wrinkles and other common signs of aging also start to appear and can make you look older than you really are. To avoid this, preventive measures such as using the most potent anti-aging creams you can find should be undertaken. On the other hand, in this day and age of media saturation, it can be quite overwhelming and equally difficult to determine which one really is the best wrinkle cream in the market.

Ideally, the best wrinkle cream not only addresses wrinkles, but also other signs of aging such uneven complexion, dullness, fine lines, and sagging among others. To make finding the best wrinkle cream for you, below you can find a list of some of the ingredients used in the most popular and effective anti-wrinkle creams.

Vitamin A derivatives

Specifically Retinol, this vitamin A compound is the first ever antioxidant to be popularly used in non-prescription wrinkle creams, acne creams, and anti-aging creams. Retinol is capable of neutralizing free radicals that causes your skin cells to break down, which in turn cause wrinkles. It also helps in increasing cell turnover for faster skin renewal.

On the other hand, Tretinoin, a more potent vitamin A derivative is approved by the FDA, or Food and Drug Administration to treat wrinkles, and works just like Retinol, but is only available by prescription. Those who are pregnant or planning to get pregnant should avoid vitamin A derivatives at all costs since these can increase chances of birth defects.

Bioactive Keratin

Sourced from the wool of sheep, bioactive keratin is similar to the primary keratin protein compound found in your skin. It aids in stimulating the re-growth of fresh skin cells, trapping moisture in your skin, and encouraging the regeneration of elastin and collagen to combat wrinkles.


DMAE or Dimethylaminoethenol is a potent antioxidant that makes your face firmer for a more youthful look. It works by regulating the movement of your face’s skeletal muscles which in turn makes your skin more elastic and firm. It can likewise improve muscle function to give your face contours more definition. It also aids in preventing and reducing discoloration.

Scientific studies state that anti-wrinkle creams that combine both DMAE and ALA, or alpha lipoic acid are more potent.


ALA or Alpha Lipoic Acid is a powerful antioxidant used not only in skin care preparations but for specific diseases as well. Researches show that it is capable of bringing about a ‘recycling’ effect on antioxidants such as CoQ10 and vitamin c. It can likewise neutralize free radicals in the cells’ watery and fatty regions, and this ability is unique since most antioxidants only have neutralizing effects in one region.


Peptides are tiny fragments of protein capable of promoting the skin cells’ production of elastin and collagen. One example of this is Argireline, a peptide capable of relaxing facial muscles, thereby leading to less facial tension which greatly contributes to the formation of wrinkles and fine lines. Specifically, Argireline’s effects are comparable to those of BOTOX.


GABA or Gama-aminobutyric acid is an amino acid capable of acting as a neurotransmitter in the CNS or central nervous system. Similar to BOTOX and Argireline, GABA has the ability to reduce facial tension by making your facial muscles relax, which in turn prevents wrinkles from forming.

Hyaluronic Acid

Hyaluronic Acid, also called Hyaluronan, fights wrinkle formation by drawing moisture and retaining the moisture it gets from the air by as much as 1000 times of its weight in water in order to effectively hydrate your skin and prevent wrinkles and fine lines. It is in the body in high amounts, most notably in connective tissues where it serves as a lubricant and a cushion.


A lipopeptide, Matrixyl is a fatty acid combined with amino acids, with the active compound Micro-collagen, which is another peptide. It is capable of stimulating the skin’s matrix layers, mainly fibronectin and collagen. It is also presently found in high end anti-aging, wrinkle, and skin care preparations. Reportedly, it can effectively mimic the effects of BOTOX and is touted to replace BOTOX in the years to come. Its potency can be further enhanced when used with other peptides.


CoQ10, also called Coenzyme Q10 or ubiquinone is an essential nutrient capable of helping the regulation of your cells’ energy production. As an antioxidant, CoQ10 also protects the skin from free radicals and reduce the formation of fine lines and wrinkles. Some studies also state that it can protect the skin from photo damage.


As stated above, antioxidants protect the skin from free radicals that cause skin damage and other aging signs. Some of the more common antioxidants found in anti-wrinkle creams include vitamin C, vitamin A, and green tea extract.

These are just some of the more common ingredients found in the best wrinkle cream products out in the market today. Undoubtedly, there are plenty more and there will be more to come. When looking for the best wrinkle cream, you should ideally find one that contains sufficient amounts of topnotch quality ingredients, safe for overall health, and fine enough so it will be capable of penetrating your skin.

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